Antibiotics May Raise Diabetes Risk

A new study has indicated that people that take multiple rounds of antibiotics could have an increased risk of developing both Type 1 and Type 2 diabetes. The risk may be caused by alterations of the gut microbiota. The discovery was made by a research team at the University of Pennsylvania, Philadelphia. The researchers, lead by Ben Boursi, MD, discovered that the risk of diabetes was higher by up to 37%, which depends on the antibiotics and number of courses.


The study was published to the European Journal of Endocrinology. The studies were done in both animals and humans and have indicated that the gut microbiota changes when it is exposed to antibiotics. In mice, lose doses of penicillin can cause obesity.


There are also additional studies that show that show that exposure to antibiotics in early childhood can result in a higher risk of developing obesity later on. The latest study was done using records from the Health Improvement Network (THIN), which is a UK population-based database. The findings indicated highest risk for diabetes was for people that had undergone more than five rounds of quinolones. The study looked at patients who had takenpenicillin, cephalosporins, macrolides, or quinolones.


When looking at compounds other than antibiotics, the researchers were unable to locate a connection between diabetes risk and treatment with imidazole, antiviral drugs, and antifungals, regardless of the number of courses.

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