Dextromethorphan Could Help With Type 2 Diabetes
Dextromethorphan which is an ingredient in over-the-counter cough suppressants could be helpful in the fight against Type 2 diabetes. Researchers at Heinrich Heine University in Düsseldorf, Germany have discovered that the drug can increase the release of insulin as a result of studies performed on mice and humans. Dextromethorphan could be especially promising because it has less side-effects than other drugs that are currently being used to treat Type 2 diabetes.
Type 2 diabetes is a condition that affects roughly 349 million people around the world according to statistics from the World Health Organization. One of the major challenges of fighting diabetes has been the fact that the blood sugar levels are often difficult to regulate in patients due to a lack of insulin sensitivity. The researchers say that they made the discover by accident. They ended up finding that a compound known as dextrorphan forms in the body when the patient ingests dextromethorphan, which leads to an increase of insulin from the pancreas. The findings also indicate that NMDA receptors in the pancreas enhances glucose-stimulated insulin secretion, which is the method by which dextromethorphan suppresses a cough when taken for a cold.
The researchers say that more testing needs to be done because the findings are the results of only a single clinical trial. They are currently hoping that researchers will try further trials at established diabetes centers.